Folligon

DogsRabbitsCattleSheepGoatsOstriches

Product class

Folligon

Folligon has an activity which is broadly similar to Follicle Stimulating Hormone (FSH) and Luteinising Hormone (LH).


Composition 

  • Freeze dried product: PMSG (Pregnant Mare Serum Gonadotrophin), mannitol, disodium hydrogen phosphate 2aq.
  • Diluent: water for injection.
       

Formulation  
Freeze dried product with diluent. 

Indications  

Females:

  • anoestrus (oestrus induction and to increase ovarian activity leading to improved fertility (cows, rabbit, bitches, mink) 
  • superovulation (required for embryo transplantation cows, rabbit, deer) 
  • to improve fertility after progestagen oestrus synchronisation, to increase ovarian activity) (cows, goat, sheep, deer)   

Males:

  • Impaired spermatogenesis   


Dosage    

FemalesIndicationDosage
CattleAnoestrus/oestrus induction*500 - 1,000 IU
CattleSuperovulation1,500 - 3,000 IU, i.m. between day 8 - 13 of the cycle, followed by 3 ml Prosolvin, i.m 48 hours
CattleTo increase fertility rate after progestagen treatment
 		300 - 750 IU, i.m., at the end of a progestagen treatment
BitchAnoestrus / oestrus induction500 IU/animal or 20 IU/kg bodyweight per day for 10 days, i.m., at day 10 injection of 500 IU hCG.
GoatTo increase fertility rate after progestagen treatment (in and out of the breeding season)
 		400 - 750 IU, i.m., at the end of a progestagen treatment
RabbitAnoestrus / oestrus induction Superovulation
40 IU, i.m. or s.c.
SheepTo increase fertility rate after progestagen treatment (in and out of the breeding season)400 - 750 IU, i.m., at the end of a progestagen treatment
MinkAnoestrus / oestrus induction100 IU, i.m., twice with an interval of 2 days
Deer

To increase of fertility rate after progestagen pre-treatment

200 IU, i.m., at the end of a progestagen treatment
Superovulation200 IU, i.m., in combination with 0.5 unit FSH

* Anoestrus is often caused by inadequate management (feeding and housing). Therefor improvement of management is a pre-requisite for a successful treatment.
 
Withholding period  
None. National regulations should be observed

Presentation  
5 x 1000 IU vials with diluent.

Storage  
Store freeze dried product at 8-15°C for and after reconstitution at 2-8°C. Protect from light.

Contra-indications  
Rare anaphylactoid reactions may occur: adrenaline (1:1000) may be injected i.v. or i.m. when such symptoms appear.